Step-by-Step Guide to Operate a Stability Chamber by Pacorr

Pacorr Stability Chamber is a highly reliable and precise testing instrument used to simulate various environmental conditions to assess product durability, shelf life, and stability. Designed for pharmaceutical, cosmetic, food, electronics, and chemical industries, this equipment plays a crucial role in quality control by exposing products to controlled temperature and humidity over time. With user-centric design, robust build quality, and digital controllers, Pacorr’s Stability Chamber ensures consistent and repeatable testing results for accelerated aging studies and long-term storage analysis.

This step-by-step guide explains how to correctly install, calibrate, and operate the Stability Chamber, ensuring optimal use while maintaining safety and efficiency. Whether you're a lab technician, QA specialist, or a production engineer, following these best practices will help you maximize the effectiveness of this advanced testing device.

What is a Stability Chamber?

A Stability Chamber is a laboratory testing device designed to mimic specific climatic conditions such as controlled humidity, temperature, and sometimes light. These chambers are essential for stability testing of drugs, chemicals, cosmetics, and food products. They allow manufacturers to determine how environmental stress impacts the quality, integrity, and longevity of a product over time.

Key Features of Pacorr Stability Chamber

• Precision digital controllers for temperature and humidity
• Double-walled insulation for thermal stability
• Safety alarms for temperature deviation and power failure
• Humidity generation via water reservoir or steam
• LED indicators and user-friendly interface
• Data logging and USB output for recording test results
• Adjustable stainless steel trays for sample placement
• Conforms to ICH, FDA, and other industry standards

Applications of Stability Chamber in Industries

• Pharmaceuticals: Stability testing of tablets, capsules, syrups under ICH zones I-IV conditions
• Food and Beverage: Assessing shelf life and packaging durability
• Cosmetics: Evaluating formulation stability under heat and humidity
• Electronics: Testing performance of devices/components in varying climates
• Chemicals: Observing chemical reaction behavior over prolonged periods

Step-by-Step Guide to Operate Pacorr Stability Chamber
 

Step 1: Pre-Installation Checklist

Before you begin the operation, ensure the following:

• The chamber is placed in a vibration-free, well-ventilated environment
• There is a dedicated power supply line with proper grounding
• No direct exposure to sunlight or heat sources nearby
• The water reservoir (if applicable) is filled with demineralized water
• Ensure all packaging and protection materials are removed

• Plug the unit into the power supply
• Switch ON the main power button at the control panel
• Wait for the digital display to activate and run its self-check
• Observe if all safety indicators and lights are functioning properly

1. Navigate to the control panel interface
2. Select ‘Set Parameters’ option
3. Enter the required temperature value (e.g. 40°C) using the arrow keys
4. Enter the desired relative humidity (e.g. 75%)
5. Confirm settings and press ‘Start’
6. The chamber will begin conditioning to the set environment

Pro Tip: Use recommended ICH stability testing conditions like:

• 25°C ± 2°C / 60% RH ± 5% RH (long-term)
• 30°C ± 2°C / 65% RH ± 5% RH (intermediate)
• 40°C ± 2°C / 75% RH ± 5% RH (accelerated)

• Open the chamber door once the internal environment has stabilized
• Place the samples evenly spaced on trays to allow proper airflow
• Avoid overcrowding to prevent inaccurate results
• Ensure sample containers are clean, sealed, and properly labeled

Important: Do not frequently open the chamber door during operation, as it may disturb the internal climatic conditions.

• After placing the samples, close the chamber door securely
• Monitor the display to ensure temperature and humidity remain consistent
• Let the test run for the desired period (ranging from hours to months)
• Record data periodically using the chamber’s USB data logger or software system

Optional Feature: Use integrated alarms and notifications to alert in case of environmental deviations or equipment malfunctions.

• Once the test duration is complete, turn off the heating/cooling module
• Open the chamber door slowly to avoid sudden exposure to external conditions
• Carefully remove test samples for further analysis
• Save or export logged data for documentation and comparison
• Turn off the main power switch and clean the chamber if needed

Routine maintenance ensures long-term performance and durability of your Pacorr Stability Chamber.

• Clean internal chamber walls with a soft cloth and mild disinfectant
• Inspect the humidity reservoir and refill as needed
• Replace or clean filters monthly
• Calibrate temperature and humidity sensors every 3–6 months using certified calibration tools
• Schedule professional service annually or based on usage

Best Practices for Using a Stability Chamber

• Avoid overloading trays with samples
• Use only distilled or deionized water to prevent mineral build-up
• Maintain a test logbook to track each test cycle
• Periodically check alarm systems and backup batteries
• Verify environmental uniformity with separate external sensors if required

• Experience: Trusted by professionals across pharmaceutical and food industries
• Expertise: Designed with advanced engineering for accurate testing results
• Authoritativeness: Conforms to major regulatory standards (ICH, FDA, ISO)
• Trustworthiness: Proven performance in long-term and accelerated testing environments

Pacorr Stability Chamber offers an advanced and dependable solution for conducting environmental testing with unmatched precision. This guide ensures users can confidently operate the chamber from installation to final reporting. By adhering to proper protocols, following calibration practices, and understanding the functional logic of the machine, users can maintain high-quality results and ensure product compliance with regulatory guidelines.

Whether you're testing drug stability for regulatory submission or evaluating packaging performance under tropical conditions, Pacorr Stability Chamber remains the ideal choice for robust, repeatable, and professional-grade testing.